Chapter 9 of 21 · Theme: Clinical AI: Diagnosis and Prediction

The Origami of Life and the Nobel Prize for Precision

AlphaFold (2024 Nobel Prize in Chemistry) and pharmacogenomics; "N-of-1" personalized medicine.

The chapter explains, in accessible language, the impact of AlphaFold, awarded the 2024 Nobel Prize in Chemistry, on our ability to predict the three-dimensional structure of proteins: a decades-old scientific problem solved by AI in a matter of years. From there, the authors connect this advance to pharmacogenomics and the idea of "N-of-1" personalized medicine: treatments designed from the genetic and molecular profile of a single patient rather than average population protocols, pointing to a future in which each person may be, in a sense, their own clinical trial.

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